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-  2018 

miR-29b enhances prostate cancer cell invasion independently of MMP-2 expression

DOI: 10.1186/s12935-018-0516-0

Keywords: Prostate cancer, Matrix metalloproteinases, Collagen, microRNA

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Abstract:

qRT-PCR. There was significant expression of collagen genes after transfection of DU-145 cells with a miR-29b inhibitor. COL1A1 increased 248% (b) and COL3A1 86% (d) after miR-29b inhibition. However, miR-29b mimics showed no difference in collagen expression (a and c). The Y axis represent the relative expressions of COL1A1 and COL3A1 mRNA

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