MiR-1180 from bone marrow MSCs promotes cell proliferation and glycolysis in ovarian cancer cells via SFRP1/Wnt pathway

BM-MSCs promotes ovarian cancer cell proliferation. a, b SKOV3 and COC1 ovarian cancer cell proliferation was assayed by MTT method. SKOV3 and COC1 cells were exposed to BM-MSCs-CM for 24 h. Cell survival rates were analyzed at 1, 2, 3, 4 and 5 days. c, d SKOV3 and COC1 ovarian cancer cell survival ability was assayed by colony formation assay. SKOV3 and COC1 cells were treated with BM-MSCs-CM for 24 h, and then seeded in 6 cm culturing plates. The cells were cultured for 10 days and the colonies were counted. The up panels showed the photos of the colony and the low panels showed the analyzed data of the colony numbers from the photos. **p？<？0.01; *p？<？0.0