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-  2019 

miR-182-5p affects human bladder cancer cell proliferation, migration and invasion through regulating Cofilin 1

DOI: 10.1186/s12935-019-0758-5

Keywords: miR-182-5p, Bladder cancer, Cofilin 1, Proliferation, Migration, Invasion

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Abstract:

Cofilin 1 upregulates in bladder tumor tissues and cell lines. a Cofilin 1 mRNA expression in bladder tumor and homologous para-tumor tissues were measured by qRT-PCR. b Cofilin 1 protein expression in bladder tumor (T) and homologous para-tumor (N) tissues were measured by Western blotting. c, d Cofilin 1 mRNA and protein expression in bladder cancer cell lines (RT4 and T24) and normal bladder epithelial cell line (SV-Huc-1) measured by qRT-PCR and Western blotting. ** Indicates p?<?0.01, ***indicates p?<?0.00

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