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-  2018 

MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma

DOI: 10.1186/s12935-018-0694-9

Keywords: miR-770, CDK8, Glioma, Proliferation, Cell cycle

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Abstract:

miR-770 is downregulated in glioma tissues and cell lines. a miR-770 expression was remarkably decreased in glioma tissues compared with that in adjacent normal tissues. b MiR-770 expression was significantly reduced in glioma cell lines (SNB19, LN229, U87 and U251) compared with that in normal human astrocyte (NHA) cells. *p?<?0.0

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