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-  2017 

The Role of Notch1 Signaling in Anaplastic Thyroid Carcinoma

DOI: 10.4143/crt.2016.214

Keywords: Receptor Notch1, Anaplastic thyroid carcinoma, Papillary thyroid cancer, Epithelial-mesenchymal transition, Neoplastic stem cells

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Abstract:

The Notch signaling pathway is widely expressed in normal, reactive, and neoplastic tissues; however, its role in thyroid tissues has not been fully elucidated. Therefore, this study was conducted to characterize the expression of the Notch signaling pathway in papillary thyroid cancer (PTC) cells and anaplastic thyroid cancer (ATC) cells

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