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- 2017
T-cadherin deficiency increases vascular vulnerability in T2DM through impaired NO bioactivityDOI: 10.1186/s12933-016-0488-0 Keywords: Endothelial cell, Endothelial dysfunction, T-cadherin, T2DM, NO bioactivity, Vascular ring Abstract: Endothelial dysfunction plays a critical role in the development of type 2 diabetes (T2DM). T-cadherin (T-cad) has gained recognition as a regulator of endothelial cell (EC) function. The present study examined whether T-cad deficiency increases vascular vulnerability in T2DM
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