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OALib Journal期刊
ISSN: 2333-9721
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-  2017 

LOW O6–METHYLGUANINE-DNA METHYTRANSFERASE (MGMT) AND PAN-CYTOKERATIN (PAN-CK) EXPRESSION VIA IMMUNOHISTOCHEMISTRY IN PITUITARY ADENOMAS

DOI: 10.4183/aeb.2017.282

Keywords: pituitary adenoma, invasiveness, MGMT, cytokeratin, Ki-67, p53, immunohistochemistry

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Abstract:

Pituitary adenomas (PA) are the third most common intracranial tumors, with an incidence rate of 10-15%. More than half are invasive, infiltrating adjacent structures. The primary objective of this project was to determine whether MGMT expression is associated with the invasiveness of PA

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