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-  2019 

The effect of nonbenzodiazepines sedative hypnotics on apnea–hypopnea index: A meta-analysis

DOI: 10.4103/atm.ATM_198_18

Keywords: Apnea–hypopnea index, continuous positive airway pressure, eszopiclone, nonbenzodiazepine sedative hypnotics, obstructive sleep apnea, placebo, zolpidem, zopiclone

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Abstract:

Nonbenzodiazepine (non-BZD) sedative hypnotics (NBSH) refer to non-BZD sedatives that act as BZD receptor agonists such as zolpidem, zaleplon, and eszopiclone. Today, there is a high prevalence of insomnia with or without concurrent obstructive sleep apnea (OSA). Our goal was to study how NBSH use impacts the baseline apnea–hypopnea index (AHI) in patients with or without OSA

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