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-  2017 

Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults

DOI: 10.1016/j.trci.2017.06.004

Keywords: Anticholinergic medication, Alzheimer's disease, Brain atrophy, Cortical thickness, Longitudinal change, Brain aging, Midlife

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Abstract:

We examined how long-term anticholinergic (AC) drug use beginning at midlife affects risk of Alzheimer's disease (AD) and rates of brain atrophy in cognitively normal older adults

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