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- 2018
Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's diseaseDOI: 10.1016/j.dadm.2017.11.001 Keywords: Alzheimer's disease, Cerebrospinal fluid, Dementia, Dopamine, Down syndrome, Monoamines, MHPG, Neurotransmitter, Noradrenaline, Plasma, Serotonin, Trisomy 21 Abstract: People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS
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