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-  2017 

Human endogenous retroviruses and chosen disease parameters in morphea

DOI: 10.5114/ada.2017.65621

Keywords: human endogenous retroviruses, real-time polymerase chain reaction, autoimmunity, localized scleroderma, skin

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Abstract:

Morphea (localized scleroderma) is a relatively rare disease characterized by excessive skin fibrosis. Human endogenous retroviruses (HERV) are largely distributed within the human genome with hundreds of thousands of elements. The HERV have been widely studied in autoimmune disorders, yet hardly ever assessed in diseases with a good prognosis such as morphea

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