Sweet’s syndrome with idiopathic epididymitis

Sweet’s syndrome (SS), also known as acute febrile neutrophilic dermatosis, is a rare condition presenting with an abrupt onset of fever and tender skin lesions with neutrophilic infiltration in the dermis, accompanied by leukocytosis [1]. Although it is not always possible to determine the etiology, SS most commonly arises as a consequence of systemic disorders. Approximately 20% of SS cases are associated with solid tumor or hematologic malignancy, most often acute myelogenous leukemia [2–5]. Cases of drug-induced SS were described after exposure to a wide variety of medication, including granulocytecolony stimulating factor [6] and other anticancer agents, antibiotics, antiepileptic, antidepressant, antihypertensive drugs, and oral contraceptives [5–8]. Pharmacotherapy-associated SS accounts for approximately 12% of SS cases [3]. The classic (idiopathic) SS type may occur in association with infections, autoimmune disorders or pregnancy [4, 9]