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-  2018 

Retinal thickness correlates with parietal cortical atrophy in early-onset Alzheimer's disease and controls

DOI: 10.1016/j.dadm.2017.10.005

Keywords: Optical coherence tomography (OCT), Retinal thickness, Biomarker, Alzheimer's disease, Retina, Cortical atrophy

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Abstract:

The retina may reflect Alzheimer's disease (AD) neuropathological changes and is easily visualized with optical coherence tomography (OCT). Retinal thickness decrease has been correlated to AD, however, without information on amyloid status. We correlated retinal (layer) thickness to AD biomarkers in amyloid-positive early-onset AD (EOAD) patients and amyloid-negative controls

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