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OALib Journal期刊
ISSN: 2333-9721
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-  2019 

Immediate hypersensitivity to polyethylene glycols in unrelated products: when standardization in the nomenclature of the components of drugs, cosmetics, and food becomes necessary

DOI: 10.1186/s13223-019-0327-4

Keywords: Excipient allergy, Anaphylaxis, Basophil activation test, Hypersensitivity, Polyethylene glycol

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Abstract:

Skin prick test and basophil activation test results. Skin prick test (left): a cough syrup GripaNait?, containing paracetamol, dextromethorphan, doxylamine, and macrogol 6000; b PEG 1500 1% and 10% (negative), and PEG 4000 1% (positive). Basophil activation test results (right): Q2-1 represents activated basophils CD63+IgE+ (% indicated) and Q4-1 represents non-activated basophils CD63?IgE+. Positive control used anti-IgE antibody and negative control used isotonic solutio

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