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-  2019 

Genetic features associated with 18F-FDG uptake in intrahepatic cholangiocarcinoma

DOI: 10.4174/astr.2019.96.4.153

Keywords: Cholangiocarcinoma, Fluorodeoxyglucose F18, Positron-emission tomography, Gene expression, Cell cycle

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Abstract:

In intrahepatic cholangiocarcinoma (iCCA), genetic characteristics on 18F-fluorodeoxyglucose (18F-FDG)-PET scans are not yet clarified. If specific genetic characteristics were found to be related to FDG uptake in iCCA, we can predict molecular features based on the FDG uptake patterns and to distinguish different types of treatments. In this purpose, we analyzed RNA sequencing in iCCA patients to evaluate gene expression signatures associated with FDG uptake patterns

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