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- 2018
Potential Cost-Savings with Once-Daily Aminomethylcycline Antibiotic versus Vancomycin in Hospitalized Patients with Acute Bacterial Skin and Skin Structure InfectionsKeywords: acute bacterial skin and skin structure, aminomethylcycline, antibiotics, cost-savings, economic modeling, hospitalized patients, hospital stay, infections, inpatient cost, intravenous, omadacycline, outpatient cost, skin infections, vancomycin Abstract: Omadacycline is an oral and intravenous (IV) once-daily aminomethylcycline antibiotic that was recently approved by the US Food and Drug Administration for the treatment of patients with acute bacterial skin and skin structure infections (ABSSSI). In 2 phase 3 clinical trials, IV-to-oral switch and oral-only administration of omadacycline achieved the primary end points of noninferiority compared with linezolid in treating patients with ABSSSI
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