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-  2019 

Association Between Epithelial Cytokines and Clinical Phenotypes of Elderly Asthma

DOI: 10.4168/aair.2019.11.1.79

Keywords: Asthma, older adults, epithelial cells, interleukin-33, interleukin-31, eotaxin-2, TGF-beta1

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Abstract:

Asthma in the elderly has different clinical features including more severe phenotypes with higher comorbidities. Epithelial cells are known to initiate innate/adaptive immune responses in asthmatic airways. We investigated clinical features and epithelial derived cytokine levels in elderly asthmatics compared to non-elderly asthmatics in a cross-sectional cohort of adult asthmatics in order to further understand its pathogenic mechanisms

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