OALib Journal期刊
ISSN: 2333-9721
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Discovery of Aryl Sulfonamides as Isoform-Selective
Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models
DOI: 10.1021/acsmedchemlett.5b00447
Brian S. Safina, C. Lee Robinette, Charles J. Cohen, Christoph M. Dehnhardt, Clint Young, Daniel P. Sutherlin, David Bogucki, Girish Bankar, Ivan Hemeon, J. P. Johnson, Jr., Jae H. Chang, Jodie Pang, Luis E. Sojo, Matthew Waldbrook, Maxim Dauphinais, Michael
E. Grimwood, Navjot Chahal, Noah Shuart, Paul Bichler, Rainbow Kwan, Renata M. Oballa, Shifeng Liu, Sophia Lin, Sultan Chowdhury, Tarek
S. Mansour, Thilo Focken
Keywords: Sodium channel, NaV1.7, NaV1.5, pain, aryl sulfonamide, formalin model, cold allodynia
Abstract:
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