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-  2018 

Congenital morphea profunda in a 7-year-old male patient with coexistence of fibrous hamartoma of infancy: a rare case report

DOI: 10.5114/ada.2018.77617

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Abstract:

Scleroderma is a rare spectrum of fibrosing disorders ranging from systemic sclerosis to localized scleroderma (morphea). The etiology is believed to involve activation of fibroblasts, increased production of collagen, and immunologic abnormalities [1]. The incidence of localized scleroderma is around 0.3 to 3 cases per 100 000 inhabitants/year. The prevalence of morphea is similar in children and adults. The peak incidence occurs in the fifth decade of life in adults, whereas 90% of children are diagnosed with the disease between 2 and 14 years of age [2]

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