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-  2016 

Preliminary Screening of a Classical Ayurvedic Formulation for Anticonvulsant Activity

DOI: 10.4103/0257-7941.195410

Keywords: Antioxidant, Ayurvedic formulation, epilepsy, GABA, pentylenetetrazole

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Abstract:

Epilepsy is a serious and complex central nervous system disorder associated with recurrent episodes of convulsive seizures due to the imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) neurotransmitters level in the brain. The available treatments are neither competent to control the seizures nor prevent progress of disease. Since ages, Herbal medicines have remained important sources of medicines in many parts of world which is evidenced through their uses in traditional systems of medicine i.e. Ayurveda, Siddha, Unani, Homeopathy and Chinese etc

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