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-  2018 

AMPK promotes the survival of colorectal cancer stem cells

DOI: 10.1002/ame2.12016

Keywords: AMP‐activated protein kinase, cancer metabolism, colorectal cancer stem cells, patient‐derived xenograft

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Abstract:

Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females worldwide in 2012. In the past 20 years, strong evidence suggests that cancer stem cells are the main culprit of cancer metastasis, chemotherapy resistance, and relapse

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