Unmasking the benefits of donepezil via psychometrically precise identification of mild cognitive impairment: A secondary analysis of the ADCS vitamin E and donepezil in MCI study

DOI: 10.1016/j.trci.2017.11.001

Keywords: Mild cognitive impairment, MCI, Alzheimer's disease, Dementia, Donepezil, Treatment, Neuropsychology, Misdiagnosis, False positive, Cluster analysis

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Abstract:

Criteria for mild cognitive impairment (MCI) used in many clinical trials are susceptible to “false-positive (FP)” errors that can be avoided by an actuarial psychometric approach

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