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- 2018
Nanotechnology-Based Cancer Treatments SciDoc Publishers | Open Access | Science Journals | Media PartnersDOI: http://dx.doi.org/10.19070/2167-8685-120001e Keywords: n/a Abstract: Cytotoxicity limits the potential of high molecular weight cationic polymers in gene delivery. About 100 years ago, this realization in the western world led to the study of biochemical interactions; a ma -jor change in the prevailing paradigm used to explain cellular functions and disease progression. The phar-maceutical industry eventually became very successful in using chemicals to develop a series of drugs and transformed medicine into a huge multibillion business selling drugs. All the research dollars and effort are mostly directed towards understanding the chemistry of the body and developing drugs to alter that chemistry. Yet many biological questions remain unanswered as evidenced by the millions of cancer deaths worldwide each year and the number is only growing. It is clear that all questions of the body can -not be answered by chemistry (drugs) only and the biochemical processes do not explain the electrical functions and electrostatic forces and their interactions in cell regulations and hence in deadly diseases like cancer. Our body possesses electrical mechanisms and use charges and electricity to regulate and control the transduction of chemical energy and life processes. Hence, there is a critical need for alter-nate/additional therapies and nanotechnology could pave a way towards this and the combination of na -nosecond electrical pulses with (and without also) drugs offers other ways to treat some of the cancers that are refractory to the current standard of cure
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