Investigation of The Malondialdehyde, Antioxidant Enzymes, Antioxidant Substance

Abstract Actinomycosis is commonly known as “lumpy jaw” that is a specific disease characterized with mandibular osteomyelitis in cattle. In our study, malondialdehyde, superoxide dismutase and some biochemical parameter levels in cattles with Actinomycosis were investigated. Thirty cattle were used in this study. 15 number of these were used as a control group of healthy individuals. Out of fifteen were Actinomycosis group. Statistical analysis showed that, concentrations of malondialdehyde were higher (P<0.001) and superoxide dismutase concentrations were lower (P<0.001), catalase, glutathione peroxidase and glutathione levels were significantly lower (P<0.01) in the cattles with Actinomycosis than in healthy ones. Glucose, cholesterol and LDL levels were significantly increased (P<0.001), HDL levels were significantly decreased (P<0.001) in the Actinomycosis group according to control group. Triglyceride concentrations were markedly increased (P<0.01) and albumin concentration was decreased (P<0.01). The enzyme activities of ALT were significantly increased (P<0.05) and as to AST enzyme’s activities were decreased (P<0.05). There was no statistically significant differences for the total protein levels in the Actinomycosis Group