Are Beta Phase-Coupled High-Frequency Oscillations and Beta Phase-Locked Spiking Two Sides of the Same Coin?

Changes of oscillatory patterns in the basal ganglia and in subcortico-cortical motor loops are a hallmark of Parkinson's disease (PD; [Hammond et al., 2007][1]). However, the neuronal mechanisms underlying these spectral dynamics and how they contribute to motor symptoms remain to be clarified.