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-  2016 

局部晚期鼻咽癌新辅助化疗研究进展

DOI: 10.3971/j.issn.1000-8578.2016.02.001

Keywords: 新辅助化疗,鼻咽癌,同步化疗,调强放疗,Effect of Neoadjuvant Chemotherapy Cycles on Pathologic Complete Response Rate Under Different Estrogen Receptor Status of Breast Cancer,Efficacy of IMRT Combined with Capecitabine Concurrent Chemotherapy and High Intensity Focused Ultrasound for Elderly Patients with Non-operatable Pancreatic Cancer,Comparison of Long-term Efficacy of IMRT plus Concurrent Chemotherapy Versus Neoadjuvant Chemotherapy Followed by IMRT plus Concurrent Chemotherapy for Locoregionally Advanced Nasopharyngeal Carcinoma,Correlation Between Skull Base Invasion and Bone Metastases in Locally Advanced Nasopharyngeal Carcinoma Patients,Construction of RNAi Targeting CLU Gene and Effect of CLU on Biological Function of Nasopharyngeal Cancer Cells,Risk Factors Associated with Hematologic Toxicity in Concurrent Chemoradiotherapy and IMRT for Cervical Cancer,Effect of 5-Azacytidine on hTERT mRNA Expression and Telomerase Activity in Human Nasopharyngeal Carcinoma Cells,Relationship Between Bladder and Rectum Volume and Its Absorbed Dose of Radical Intensity Modulated Radiotherapy on Cervical Cancer,Valuation of SUVmax, Ki-67, p53 and EGFR in Predicting Effect of Neoadjuvant Chemotherapy on Triple-negative Breast Cancer Patients,Expression of Annexin A2 in Nasopharyngeal Carcinoma Tissues and Its Clinical Significance,Trends on Morbidity of Nasopharyngeal Carcinoma Among Residents in Pudong New Area of Shanghai, 2002-2013,Tumor-infiltrating Lymphocytes Predict Response to Neoadjuvant Chemotherapy in Patients with Breast Carcinoma,Platinum Resistance after Neoadjuvant Chemotherapy Interval Debulking Surgery Compared with Primary Debulking Surgery on Patients with Advanced Epithelial Ovarian Carcinoma,Advances of Dose-painting Radiotherapy,Effects of High Mobility Group Box-1 Protein on Migration and Invasion Ability of Nasopharyngeal Carcinoma Cell Line C666-1 in vitro

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Abstract:

摘要 鼻咽癌的治疗手段是以放射治疗为主的综合治疗,随着调强放疗等精确放疗技术和放化综合治疗的广泛应用,初治鼻咽的局部控制率已经提高到90%以上。为了提高局部晚期鼻咽癌的治愈率、降低复发或远处转移,放疗与化疗的结合一直是学者们研究热点。由于同步放化疗已成为局部晚期鼻咽的标准治疗,新辅助化疗是鼻咽癌综合治疗研究的热点,新辅助联合同步放化疗是否获益一直存在争议。同时调强放疗的大量应用,同步化疗的地位受到怀疑,新辅助化疗在调强时代能否替代同步化疗及新辅助化疗后靶区应如何勾画值得进一步 研究。因此,本文就新辅助化疗治疗 局部晚期鼻咽癌的进展进行综述

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