213例ⅢB期食管胃结合部腺癌患者术后5年随访及预后分析
DOI: 10.3971/j.issn.1000-8578.2015.10.011
Keywords: Partial Versus Radical Nephrectomy,Relationship of Macrophage Migration Inhibitory Factor Expression with Clinicopathologic Features and Prognosis of Cardiac Carcinoma Patients,Advance of Prognostic Markers of Cervical Cancer,Correlation of CD68+ Tumor-associated Macrophages Number with Ki-67 Expression and Prognosis of Patients with Primary Hepatocellular Carcinoma,Prognostic Value of Circulating Tumor Cells for Metastatic Prostate Cancer: A Metaanalysis,Metaplastic Carcinoma of Breast with Mesenchymal Differentiation: 28 Cases Report,Predictive Value of C-reactive Protein/Albumin Ratio on Prognosis of Patients with Primary Hepatocellular Carcinoma,Clinical Investigation on Qingfei Mixture Combined with Chemotherapy on Middle and Advanced Non-small Cell Lung Cancer,Expression and Clinical Significance of Artemin Protein in Triple-negative and Nontriple-negative Breast Cancer Tissues,Prognosis Factors for Patients with Stage pT3N0M0 Thoracic Esophageal Squamous Cell Carcinoma after Radical Resection,Value of 21-gene Assay in Treatment Decisions for Hormone Receptor-positive Nodepositive Early Breast Cancer
Abstract:
摘要 目的 探讨Ⅲb期食管胃结合部腺癌（adenocarcinoma of esophagogastric junction, AEG）的外科治疗效果及影响预后的相关因素。方法 回顾性分析了2006年3月至2007年2月在河北医科大学第四医院胸外科接受治疗的213例ⅢB期AEG患者的临床病例资料，对患者进行了5年的随访，采用寿命表法计算患者的生存率，Kaplan-Meier法进行预后生存分析，Cox比例风险模型进行多因素分析。结果 本组根治性切除术207例、扩大性切除术3例、姑息性切除术3例。总体1年生存率为83%，3年生存率为46%，5年生存率为32%。单因素分析显示：性别、手术方式、残端是否阳性及术后化疗是影响预后的主要因素。多因素分析显示：性别（P=0.016）、手术方式（P=0.025）、术后化疗（P=0.001）及残端是否阳性（P=0.002）是影响预后的独立危险因素。结论 ⅢB期食管胃结合部腺癌的预后较差，性别、手术方式、残端是否阳性及术后化疗是独立性预后因素。综合治疗仍是提高ⅢB期食管胃结合部腺癌患者治疗效果的主要途径
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