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-  2018 

阿瑞匹坦对妇科恶性肿瘤化疗相关不良反应的影响

DOI: 10.3971/j.issn.1000-8578.2018.18.0265

Keywords: 阿瑞匹坦,化疗相关性恶心呕吐,血红蛋白,妇科肿瘤,Aprepitant versus Olanzapine for Prevention of Nausea and Vomiting Induced by Multiday Chemotherapy in Female Lung Cancer or Breast Cancer Patients,Clinical Observation of Neurokinin-1 Antagonist Preventing Multiple-day Chemotherapy-induced Nausea and Vomiting,Antiemetic Effect of Aprepitant for Cisplatin-induced Nausea and Vomiting in Melanoma Patients,Prognostic Value of Hemoglobin Level in Elderly Patients with Advanced Lung Cancer Treated with Chemotherapy,Impact of Hemoglobin(Hgb) Level on Therapeutic Effect of Radiotherapy in Cervical Cancer Patients,Clinical Application of EPO in Common Malignant Patients Receiving Chemotherapy,Influence of Peripheral Blood Hemoglobin Concentration on the Result of Radiotherapy for Esophageal Carcinoma,Influence of peripheral blood hemoglobin on the result of radiotherapy for middle-advanced cervical carcinoma,The Diagnostic Value of Urinary Monohydroxyphenyl Substances in Patients with Gynecologic Neoplasms

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Abstract:

摘要 目的 观察阿瑞匹坦治疗妇科恶性肿瘤患者化疗后恶心呕吐的疗效及对血红蛋白水平的影响。方法 收治我院85例妇科恶性肿瘤患者,根据患者止吐药物使用情况分为阿瑞匹坦组和对照组,对照组予以化疗及常规对症处理,阿瑞匹坦组在对照组的基础上加用阿瑞匹坦,观察两组恶心呕吐、血红蛋白水平以及外周血象等变化。结果 阿瑞匹坦组患者化疗后恶心、呕吐发生率低(P<0.05),但两组头晕、头痛等其他不良反应发生率差异均无明显统计学意义(P>0.05)。化疗后红细胞数下降的程度稍轻于对照组(P>0.05)。结论 阿瑞匹坦不仅可以有效预防化疗所致恶心、呕吐的发生,提高患者生活质量和治疗依从性,还可使患者尽早进食,有利于血红蛋白的生成,减弱肿瘤负荷和化疗所致贫血程度

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