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-  2016 

维生素D3与结直肠癌相关性的研究进展

DOI: 10.3971/j.issn.1000-8578.2016.04.011

Keywords: 维生素D3,结直肠癌,相关性,Preliminary Investigation About Hematokrit Forecast of Chemotherapy Tolerance of Lung Cancer Patients,Expression and Correlation of Id-1, MMP-9 and LMVD in Colorectal Adenocarcinoma Tissues,Mortality Trend of Colorectal Cancer in Kunshan City, Jiangsu Province, 1981-2014,Recent Advances of Correlation of Mismatch Repair System hMutS, hMutL Variation and Colorectal Cancer,Effect of Intensity Modulated Radiotherapy Combined with Hormonal Therapy on Fatigue in Patients with Locally Advanced Prostate Cancer,LncRNA Colorectal Neoplasia Differentially Expressed(CRNDE) Regulated Cell Proliferation and Migration in Glioma,Effect of Apolipoprotein E on Invasion and Migration of Colorectal Cancer Cells,MicroRNA-31 Expression in Colorectal Cancer and Bioinformatic Analysis of Its Predicted Target Genes,Individualized Treatment for Advanced Colorectal Cancer Patients Based on Molecular Characteristics,Serum Peptidome Patterns of Colorectal Cancer Based on Magnetic Bead Separation and Mass-spectrometry Technique,Role of Cancer-associated Fibroblasts in Occurrence and Development of Colorectal Cancer,Role of Hepatocyte Growth Factor Receptor c-met Regulating Epithelial-mesenchymal Transition in Metastasis of Colorectal Cancer,Cancer-related Fatigue in Advanced Lung Cancer Patients and Its Relationship with Inflammatory Cytokine in Serum,Virulence Gene Mutation in Seven Kindreds of Lynch Syndrome in Yunnan Province,Meta-analysis of Relationship Between Blood 25-hydroxyvitamin D Level and Colorectal Cancer

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Abstract:

摘要 越来越多的研究证据已经表明,血清中低水平的维生素D3(VD3)与较高的结直肠癌(CRC)风险相关。目前大多数的观察性研究支持血清中25-(OH)-VD3水平与CRC风险呈负相关性。然而,口服VD3或饮食中补充VD3可否改善CRC患者的总生存期,目前还存在争议。本文将对近年来VD3与CRC相关性的研究作一综述,以期有更多前瞻性的基础研究、临床研究和人群观察性研究对VD3是否对CRC的预防和治疗有价值做出澄清

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