微小RNA-320在肿瘤中的研究进展
DOI: 10.3971/j.issn.1000-8578.2015.03.021
Keywords: miRNA,miR-320,肿瘤,靶基因,Perioperative Security Evaluation of Intra-operative Radiotherapy for Recurrent Bone and Soft Tissue Sarcomas Around Pelvis,Role of CD147 and Its Ligand CypA in Hepatoma Carcinoma Hepa1-6 Cells Escaping from Immune Surveillance of T cells,Pathological and Biological Mechanisms of Radiation-induced Heart Disease,Research Progress of FGFR4 Targeted Anti-tumor Drug,NDRG2 Inhibits Migration of Breast Cancer Cells Through Upregulating PTEN Expression,Preliminary Investigation About Hematokrit Forecast of Chemotherapy Tolerance of Lung Cancer Patients,Progress on Relationship Between Posttranslational Modification Enzymes of Collagen and Tumor,Recent Advances of Relationship Between miRNA-related SNPs and Lung Cancer Susceptibility,Progress on FOXP3 Expression in Breast Cancer Cells,Comparison of Application Value of Contrast Enhanced Ultrasound and Acoustic Radiation Force Impulse Imaging in Differential Diagnosis of Benign and Malignant Renal Tumors,Effect of PTTG1 Expression on Invasion and Migration of Colon Cancer Cell SW480 and Its Possible Mechanism,Death of Malignant Tumors and Potential Years of Life Lost Among Residents in Shandong Province, 2010-2012,Cancer Incidence and Mortality in Cancer Registries in Hubei Province, 2012,Liver Cancer Incidence and Mortality Rates During Last 40 Years in Hebei Province,Molecular Classification of Common Solid Cancers
Abstract:
摘要 微小RNA（miRNAs）是一类细胞内源性表达的小分子非编码RNA，具有转录后调控基因表达的作用。近年来，在结肠癌、乳腺癌和胆管癌等多种肿瘤中发现miR-320表达下调，提示miR-320可通过抑制细胞增殖和侵袭等方式抑制肿瘤进展。对于miR-320调控的靶基因及相关信号通路的深入研究，有助于阐明肿瘤发生发展的分子机制，并有望为临床肿瘤治疗提供新的靶点。本文就miR-320在肿瘤中的研究进展作一综述
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