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DOI: 10.3971/j.issn.1000-8578.2018.17.0628
Keywords: A Scientometric Analysis,Efficacy of Definitive External-beam Radiotherapy Versus Radical Prostatectomy on Clinically Localized High-risk Prostate Cancer Patients: A Retrospective Study,A Case Report of Four Primary Malignant Tumors,Oncolytic Adenovirus RCA-TERT-Ad35 Carrying Human Telomerase Reverse Transcriptase Promoter Targets Breast Cancer Stem Cells,Research Progress of Intestinal Microbiota and Immune Checkpoint Inhibitors,Advances in Role of Cyclooxygenase 2 in Development and Progression of Cancer,Dedifferentiated Liposarcoma of Testis: A Case Report and Literature Review,A Comprehensive Review of Androgen Deprivation Therapy and Immunotherapy on Prostate Cancer,Diffusion-weighted Magnetic Resonance Imaging Evaluates Salivary Gland Function Damage in Nasopharyngeal Carcinoma Patients Treated with Intensity-modulated Radiation Therapy,Research Advances on Effect of Adipose-derived Stem Cells on Biological Characteristics of Breast Cancer
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摘要 中心体相关激酶2（NIMA related kinase 2, NEK2）是细胞周期调控蛋白激酶（Never in mitosis A, NIMA）家族中的一个成员，在有丝分裂过程中发挥着重要的作用。NEK2异常表达造成的染色体不稳定性，是引发肿瘤的重要原因。同时，NEK2在人类肿瘤中普遍存在高表达的现象，使其可能成为癌症检测的一个重要标志，并且存在以NEK2作为治疗靶点的潜在可能性。本文对NEK2与癌症治疗相关研究的新进展进行综述
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