Coolifting？ Coolcell？, A New Group of Highly Effective Active Ingredients For the Reduction of Cellulite in Women - Coolifting？ Coolcell？, A New Group of Highly Effective Active Ingredients For the Reduction of Cellulite in Women - Open Access Pub

Cellulite is a very frequent clinical condition that, despite not being serious, constitutes one of the greatest aesthetic concerns of a large number of women. In recent years, some of the technologies that have allowed the development of devices and key tools in aesthetic medicine treatments have been consolidated. The aim of this article is to test the effectiveness of CoolCell？, a new treatment for cellulite that is administered with Coolifting？ technology. We included 24 women who received 8 sessions of Coolifting？ CoolCell？, one per week. Thermographic measurements were taken and satisfaction questionnaires were completed. Thermographic analysis showed a statistically significant color variation and self-assessment reports revealed that more around 75% of the subjects witnessed great or spectacular changes on their skin. DOI10.14302/issn.2640-6403.jtrr-18-2054 Cellulite or Gynoid lipodystrophy is a metabolic disorder of the subcutaneous tissue that affects 80-90% of adult women.1, 2, 3, 4, 5 It is characterized by an alteration of the skin and subcutaneous tissue of the affected areas, mainly thighs, buttocks and abdomen, in what is commonly called orange-peel.2,3 It is a very common clinical condition that, although not serious, constitutes one of the greatest aesthetic concerns of a large number of women.5 Cellulite presents a complex and multi-factorial etiology. Its physiopathology depends on very diverse aspects such as: anatomy, genetic susceptibility, hormonal changes, efficiency of lymphatic drainage or alterations in microvasculature, extracellular matrix or adipocytes.2,3Although there are various products and treatments for reduction of cellulite, none of them is definitive. For this reason and given its complexity, it is always necessary to develop new methodologies to address this metabolic disorder in the best possible way. 1, 2, 3, 4 In the last years, some of the technologies that have allowed the development of devices and key tools in aesthetic medicine treatments have been consolidated.6 Recently, the effectiveness of a device that improves the appearance of the skin by combining the therapeutic effects of avant-garde assets, pulsatile CO2 and cold has been proven.6Both the effects of CO2 on tissues and those of cold are well characterized. CO2, in addition to playing an important modulating role in some physiological processes (such as the Bohr effect7), also increases blood perfusion8, stimulates tissue oxygenation9 and reduces adiposity.10 During recent years, numerous studies have addressed its use in aesthetic medicine11,12