Investigation On Phytochemical and Antioxidant Activity of the Plant Murraya Koenigii Linn (curry Leaf) in Rajshahi, Bangladesh - Investigation On Phytochemical and Antioxidant Activity of the Plant Murraya Koenigii Linn (curry Leaf) in Rajshahi, Bangladesh - Open Access Pub

The use of herbal medicine is becoming popular day by day due to toxicity and side effects of allopathic medicines. Considering the medicinal importance of the plant Murraya koenigii Linn (Curry leaf), the antioxidant activity (AC), total phenolic content (TPC), total flavonoid content (TFC), of different fractions of methanolic extract (DIA-ion resin adsorbed fraction, chloroform, Ethyl acetate and petroleum ether) of M. koenigii were investigated. Among the fractions, DIA-ion resin-adsorbed fraction showed the highest total antioxidant activity with absorbance 2.320±06 and petroleum ether fraction showed the lowest total antioxidant activity with absorbance 1.944 at 100 mg/ml concentration. The TPC were found range between 13.285 to 17.52 mg GAE/g while the highest amount of TFC recorded among the extracts was 16.65 mg CatE/g. DPPH free radical scavenging activity of different extracts of leaves was also measured where DIA-ion resin-adsorbed fraction had the highest free radical scavenging activity with IC50 value 15.53 μg/ml. In the present study phenolic compound were found to be the predominant components in the leaves of M. koenigii indicating that they are potent antioxidant. DOI10.14302/issn.2471-2140.jaa-17-1728 Plants which, form the backbone of traditional medicines, have been used for thousands of years as a source of invaluable bioactive compounds1. In most Asian countries, herbal products play an important role to treat wounds, burns, intestinal problems, coughs, and general torpor2. The use of plants as traditional remedies, and to treat burns and wounds is an important aspect of health management and is also an efficient way to promote cheaper health care options3,4. Many researchers have reported in vitro and in vivo evidence to support various plant materials as topical anti-microbial agents to enhance wound healing5. Several indigenous plants and formulations for managing cuts, bruises, burns and wounds have been described in folkloric as well as the Ayurvedic system of medicine6,7. In Bangladesh 5,000 species of angiosperm are reported to occur8. The numbers of medicinal plants included in the ‘materiamedica’ of traditional medicine in this subcontinent now stand at about 2000. More than 500 of such medicinal plants have so far been enlisted as growing in Bangladesh9. Dhaka, Rajshahi, Shylet and Chittagong division is rich in medicinal plants8. Bangladesh is situated at the complex interface of the Indian, Himalayan and Southeast Asian biographic regions, and historically it is well-endowed with very diverse complements of