A Study On Contagious Bovine Pleuropneumonia in Khartoum State, Sudan - A Study On Contagious Bovine Pleuropneumonia in Khartoum State, Sudan - Open Access Pub

The study was carried out to investigate the occurrence of contagious bovine pleuropneumonia CBPP in Khartoum state. One-hundred twenty-two pneumonic lung tissue samples were collected from different slaughterhouses (116 samples most of which from local breed cattle) and from the field (six samples from cross breed cattle). Two-hundred and fifty-seven serum samples were collected randomly from cattle in different areas of the state. Tissue samples were cultivated using the standard mycoplasma procedures. Mmm was isolated from three pneumonic lungs collected from the field while no isolates were recovered from slaughterhouse samples. Histopathological sections from the positive samples revealed the typical picture of the CBPP which include fibrinonecrotic pneumonia within filtration of inflammatory cells and fibrin and distention of interlobular septae. One hundred and eight out of 257 serum samples were found positive for antibodies against Mmmusing complement fixation test (CFT). Findings of this study confirmed the presence of CBPP in Khartoum state by the isolation and identification of the causative agent. DOI 10.14302/issn.2575-1212.jvhc-17-1555 Contagious bovine pleuropneumonia (CBPP), which is caused by Mycoplasma mycoides subsp. mycoides (Mmm), is a highly contagious respiratorydisease primarily of cattle 1. The Pan African programme for the Control of Epizootics (PACE) has identified CBPP as the second most important transboundary disease in Africa after rinderpest. The disease represents a real problem to cattle health and production in Africa and estimates of annual losses in some countries account for 3.7 million Euros per country in the African sub-Saharan region 2. Although the disease was eradicated in many developed countries in the world, Africa is still suffering and the incidence of the disease is continuously increasing in some countries. Reasons for the persistence of CBPP in Africa include uncontrolled cattle movement, cessation of vaccination campaigns and decreased surveillances 3. The causative agent, which was first isolated by Nocard E. and Roux E. 4, is a member of the "Mycoplasma mycoides cluster". The cluster includes five biochemically and antigenically similar mycoplasma of animal importance 5. Formerly, Mmm was known as Mmm (small colony SC– type) and grouped together with Mmm (large colony LC– type) in a single subspecies. Later, the two mycoplasma, based on genetic differences, were separated in different subspecies and referred to as Mycoplasma mycoides subsp. mycoides and Mycoplasma mycoides subsp. Capri respectively