This research of study continues personal research and professional practice in the Alternative Medicine (AM) has become an attractive and a popular issue between academicians and researchers in the last decades. AM is mostly used by individuals to support or to substitute the medical treatment. The studies from different disciplines have shown that the AM use is expanding all over the world but the popularity and the types of its use remain unclear. A qualitative study was conducted by treating a patient through several kinds of AM, receiving positive feedback from the patient. The overall data shows very good improvement since the AM becomes one of their parts of life to continue surviving on this earth with lots of challenges. Herbalist and vitamin supplements are the most popular and commonly used alternative medicine methods. Most people had used alternative medicine to improve their health conditions, thus eliminating the side effects of modern treatments. To supersede and recover or heal this chronic symptom, a combination of AM will be great to encounter it such as cancer, psoriasis, epilepsy, viral fever, etc. A combination of Ganotherapy and Knowledge of Holistic Human System enhances the AM era into battling these chronic cases and creates a powerful immune system to protect against it.
References
[1]
Jin, L.S. (2010) Ganotherapy: The Miraculous King of Herbs.
[2]
Jin, L.S. (2003) Ganotherapy: Ganoderma lucidum the Miracle Mushroom, King of Herb and Herb of Kings for Health.
[3]
Xie, J., et al. (2012) Comparison of Polysaccharides from Two Species of Ganoderma Molecules.
[4]
Lindequist, U., Niedermeyer, T.H. and Jülich, W.D. (2005) The Pharmacological Potential of Mushrooms. Evidence-Based Complement Alternative Medicine, 2, 285-299. https://doi.org/10.1093/ecam/neh107
[5]
Wasson, R.G. (1968) Divine Mushroom of Immortality. Harcourt Brace Jovanovich, Los Angeles, 80-93.
[6]
Wasser, S.P. and Weis, A.L. (1999) Medicinal Properties of Substances Occurring in Higher Basidiomycetes Mushrooms: Current Perspectives. International Journal Medicinal Mushrooms, 1, 31-62. https://doi.org/10.1615/IntJMedMushrooms.v1.i1.30
[7]
Moncalvo, J.M., Wang, H.F., Wang, H.H. and Hseu, R.S. (1994) Molecular Studies in the Ganoderma lucidum Complex. In: 94’ International Symposium on Ganoderma Research, Beijing Medical University Press, Beijing, 12-13.
[8]
Ryvarden, L. (1994) Can We Trust Morphology in Ganoderma? Proceedings of Contributed Symposium, 14-21 August 1994, 19-24.
[9]
Gao, Y.H., et al. (2007) Antimicrobial Activity of the Medicinal Mushroom Ganoderma. Food Reviews International, 21, 211-229. https://doi.org/10.1081/FRI-200051893
[10]
Ansor, M., et al. (2013) Anti-Angiotensin Converting Enzyme (ACE) Proteins from Mycelia of Ganoderma lucidum (Curtis) P. Karst. BMC Complementary and Alternative Medicine, 13, Article No. 256. http://www.biomedcentral.com/1472-6882/13/256 https://doi.org/10.1186/1472-6882-13-256
[11]
Cör, D., Knez, Z. and Knez, H.M. (2018) Antitumour, Antimicrobial, Antioxidant and Antiacetylcho Linesterase Effect of Ganoderma lucidum Terpenoids and Polysaccharides: A Review. Molecules, 23, 649. https://doi.org/10.3390/molecules23030649
[12]
Ahmad, M.F. (2018) Ganoderma lucidum: Persuasive Biologically Active Constituents and Their Health Endorsement. Department of Clinical Nutrition, College of Applied Medical Sciences, Jazan University, Jazan, 507-519. https://doi.org/10.1016/j.biopha.2018.08.036
[13]
Zhong, J.J. and Xiao, J.H. (2009) Secondary Metabolites from Higher Fungi: Discovery, Bioactivity and Bioproduction. Advances in Biochemical Engineering/Biotechnology, 113, 79-150. https://doi.org/10.1007/10_2008_26
[14]
Eo, S.K., Kim, Y.S., Lee, C.K. and Han, S.S. (1999) Antiviral Activities of Various Water and Methanol Soluble Substances Isolated from Ganoderma lucidum. Journal of Ethnopharmacology, 68, 129-136. https://doi.org/10.1016/S0378-8741(99)00067-7
[15]
Oh, K.W., Lee, C.K., Kim, Y.S., Eo, S.K. and Han, S.S. (2000) Antiherpetic Activities of Acidic Protein Bound Polysacchride Isolated from Ganoderma lucidum Alone and Incombination with Acyclovir and Vidarabine. Journal of Ethnopharmacology, 72, 221-227. https://doi.org/10.1016/S0378-8741(00)00254-3
[16]
Kim, Y.S., Eo, S.K., Oh, K.W., Lee, C.K. and Han, S.S. (2000) Antiherpetic Activities of Acidic Protein Bound Polysaccharide Isolated from Ganoderma lucidum Alone and in Combinations with Interferons. Journal of Ethnopharmacology, 72, 451-458. https://doi.org/10.1016/S0378-8741(00)00263-4
[17]
Liu, J. and Ye, B.L. (2005) Possible Mode of Action of Antiherpetic Activities of a Proteoglycan Isolated from the Mycelia of Ganoderma lucidum in Vitro. Journal of Ethnopharmacology, 95, 265-272. https://doi.org/10.1016/j.jep.2004.07.010
[18]
Li, Z., Liu, J. and Zhao, Y. (2005) Possible Mechanism Underlying the Antiherpetic Activity of a Proteoglycan Isolated from the Mycelia of Ganoderma lucidum in Vitro. Journal of Biochemistry and Molecular Biology, 38, 34-40. https://doi.org/10.5483/BMBRep.2005.38.1.034
[19]
El-Mekkawy, S., Meselhy, M.R. and Nakamura, N. (1998) Anti-HIV-1 and Anti-HIV-1-Protease Substances from Ganoderma lucidum. Phytochemistry, 49, 1651-1657. https://doi.org/10.1016/S0031-9422(98)00254-4
[20]
Li, Y.Q. and Wang, S.F. (2006) Anti-Hepatitis B Activities of Ganoderic Acid from Ganoderma lucidum. Biotechnology Letters, 28, 837-841. https://doi.org/10.1007/s10529-006-9007-9
[21]
Hijikata, Y. and Yamada, S. (1998) Effect of Ganoderma lucidum on Postherpetic Neuralgia. The American Journal of Chinese Medicine, 26, 375-381. https://doi.org/10.1142/S0192415X98000415
[22]
Hijikata, Y., Yamada, S. and Yasuhara, A. (2007) Herbal Mixtures Containing the Mushroom Ganoderma lucidum Improve Recovery Time in Patients with Herpes Genitalis and Labialis. The Journal of Alternative and Complementary Medicine, 13, 985-987. https://doi.org/10.1089/acm.2006.6297
[23]
Ohno, N., Miura, N.N., Sugawara, N., Tokunaka, K., Kirigaya, N. and Yadomae, T. (1998) Immunomodulation by Hot Water and Ethanol Extracts of Ganoderma lucidum. Pharmaceutical and Pharmacological Letters, 4, 174-177.
[24]
Keypour, S., Riahi, H., Moradali, M.F. and Rafati, H. (2008) Investigation of the Antibacterial Activity of a Chloroformextract of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae). International Journal of Medicinal Mushrooms, 10, 345-349. https://doi.org/10.1615/IntJMedMushr.v10.i4.70
[25]
Yoon, S.Y., Eo, S.K., Kim, Y.S., Lee, C.K. and Han, S.S. (1994) Antimicrobial Activity of Ganoderma lucidum Extract Alone and in Combination with Some Antibiotics. Archives of Pharmacal Research, 17, 438-442. https://doi.org/10.1007/BF02979122
[26]
Tavakkoli, A., Mahdian, V., Razavi, B.M. and Hosseinzadeh, H. (2017) Review on Clinical Trials of Black Seed (Nigella sativa) and Its Active Constituent, Thymoquinone. Journal of Pharmacopuncture, 20, 179-193. https://doi.org/10.3831/KPI.2017.20.021
[27]
Boskabady, M.H., Javan, H., Sajady, M. and Rakhshandeh, H. (2007) The Possible Prophylactic Effect of Nigella sativa Seed Extract in Asthmatic Patients. Fundamental & Clinical Pharmacology, 21, 559-566. https://doi.org/10.1111/j.1472-8206.2007.00509.x
[28]
Ahmad, J., Khan, R.A. and Malik, M.A. (2009) A Study of Nigella sativa Oil in the Management of Wheeze Associated Lower Respiratory Tract Illness in Children. African Journal of Pharmacy and Pharmacology, 3, 248-251.
[29]
Abdel-Moneim, A., Morsy, B.M., Mahmoud, A.M., Abo-Seif, M.A. and Zanaty, M.I. (2013) Beneficial the Rapeutic Effects of Nigella sativa and/or Zingiber officinale in HCV Patients in Egypt. EXCLI Journal, 12, 943-955.
[30]
Onifade, A.A., Jewell, A.P. and Okesina, A.B. (2015) Seronegative Conversion of an HIV Positive Subject Treated with Nigella sativa and Honey. African Journal of Infectious Diseases, 9, 47-50. https://doi.org/10.4314/ajid.v9i2.6
[31]
Barakat, E.M.F., El Wakeel, L.M. and Hagag, R.S. (2013) Effects of Nigella sativa on Outcome of Hepatitis C in Egypt. World Journal of Gastroenterology, 19, 2529-2536. https://doi.org/10.3748/wjg.v19.i16.2529
[32]
Salem, E.M., Yar, T., Bamosa, A.O., Al-Quorain, A., Yasawy, M.I. and Alsulaiman, R.M. (2010) Comparative Study of Nigella sativa and Triple Therapy in Eradication of Helicobacter pylori in Patients with Non-Ulcer Dyspepsia. Saudi Journal of Gastroenterology, 16, 207-214. https://doi.org/10.4103/1319-3767.65201
[33]
Kessler, R.C., Davis, R.B., Foster, D.F., Van Rompay, M., Walters, E.E. and Wilkey, S.A. (2001) Long Term Trends in the Use of Complementary and Alternative Medical Therapies in the United States. Annals of Internal Medicine, 135, 262-268. https://doi.org/10.7326/0003-4819-135-4-200108210-00011
[34]
Shen, Y.C., Chen, C.F. and Chiou, W.F. (2002) Andrographolide Prevents Oxygen Radical Production by Human Neutrophils: Possible Mechanism (s) Involved in Its Anti-Inflammatory Effect. British Journal of Pharmacology, 135, 399-406. https://doi.org/10.1038/sj.bjp.0704493
[35]
Amroyan, E., Gabrielian, E., Panossian, A., Wikman, G. and Wagner, H. (1999) Inhibitory Effect of Andrographolide from Andrographis paniculata on PAF-Induced Platelet Aggregation. Phytomedicine, 6, 27-31. https://doi.org/10.1016/S0944-7113(99)80031-2
[36]
Madav, S., Tripathi, H.C., Tandan, S.K. and Mishra, S. (1995) Analgesic, Antipyretic and Antiulcero-Genic Effect of Andrographolide. Indian Journal of Pharmaceutical Sciences, 57, 121-125.
[37]
Vedavathy, S. and Rao, K.N. (1991) Antipyretic Activity of Six Indigenous Medicinal Plants of Tirumala Hills, Andhra Pradesh, India. Journal of Ethnopharmacology, 33, 193-196. https://doi.org/10.1016/0378-8741(91)90178-G
[38]
Chang, R.S., Ding, L., Chen, G.Q., Pan, Q.C., Zhao, Z.L. and Snith, K.M. (1991) Dehydrographolide Succinic Acid Monoester as an Inhibitor against the Human Immunodeficiency Virus. Proceedings of the Society for Experimental Biology and Medicine, 197, 59-66. https://doi.org/10.3181/00379727-197-43225
[39]
Ramalingam, S., Karupannan, S. and Padmanaban, P. (2018) Anti-Dengue Activity of Andrographis paniculata Extracts and Quantification of Dengue Viral Inhibition by SYBR Green Reverse Transcription Polymerase Chain Reaction. Ayu, 39, 87-91.
[40]
Puri, A., Saxena, R., Saxena, R.P., Saxena, K.C., Srivastava, V. and Tandon, J.S. (1993) Immunostimulant Agents from Andrographis paniculata. Journal of Natural Products, 56, 995-999. https://doi.org/10.1021/np50097a002
[41]
Duke, J.A. and Atchley, A.A. (1984) Proximate Analysis. In: Christie, B.R., Ed., The Handbook of Plant Science in Agriculture, CRC Press, Inc., Boca Raton, 427-434.
[42]
Nnam, N.M. and Onyeke, N.G. (2003) Chemical Compositions of Two Varieties of Sorrel Hibiscus sabdariffa L., Calyces and the Drinks Made from Them. Plant Foods for Human Nutrition, 58, 1-7. https://doi.org/10.1023/B:QUAL.0000040310.80938.53
[43]
Ojokoh, A.O. (2006) Roselle Hibiscus sabdariffa Calyx Diet and Histopathological Changes in Liver of Albino Rats. Pakistan Journal of Nutrition, 5, 110-113. https://doi.org/10.3923/pjn.2006.110.113
[44]
Adanlawo, I.G. and Ajibade, V.A. (2006) Nutritive Value of the Two Varieties of Roselle Hibiscus sabdariffa Calyces Soaked with Wood Ash. Pakistan Journal of Nutrition, 5, 555-557. https://doi.org/10.3923/pjn.2006.555.557
[45]
Carvajal, O., Maria, D., Dremitriz, B., Flores, Z.O., Margaret, P. and Jones, H. (2012) Hibiscus sabdariffa L., Roselle Calyx, from Ethnobotany to Pharmacology. Journal of Experimental Pharmacology, 4, 25-39. https://doi.org/10.2147/JEP.S27974
[46]
Olaleye, M.T. (2007) Cytotoxicity and Antibacterial Activity of Methanolic Extract of Hibiscus sabdariffa. Journal of Medicinal Plants Research, 1, 9-13.
[47]
Chao, C. and Yin, M. (2008) Antibacterial Effects of Roselle Calyx Extracts and Protocatechuic Acid in Ground Beef and Apple Juice. Foodborne Pathogens and Disease, 6, 201-206. https://doi.org/10.1089/fpd.2008.0187
[48]
Fullerton, M., Khatiwada, J., Johnson, U.S., David, S. and William, L.L. (2011) Determination of an Timicrobial Activity of Sorrel Hibiscus sabdariffa on E. coli O157:H7 Isolated from Food Veterinary and Clinical Samples. Journal of Medicinal Food, 14, 950-956. https://doi.org/10.1089/jmf.2010.0200
[49]
Leung, W.T.W., Busson, F. and Jardin, C. (1968) Food Composition Table for Use in Africa. FAO, Rome, 306 p.
[50]
Morton, J. (1987) Roselle in Fruits of Warm Climates. Web Publications Purdue University, Miami, 281-286.
