补肾调轴方调控IDO改善反复种植失败者子宫免疫微环境的研究
Study on the Improvement of Endometrial Receptance in Repeated Implantation Failure by Regulating IDO by Bushen Tiaozhou Prescription

DOI: 10.12677/HJBM.2019.92015, PP. 103-106

Keywords: 补肾调轴方，体外受精-胚胎移植(IVF-ET)，子宫免疫微环境
Bushen Tiaozhou Recipe, IVF-ET, Uterine Immune Microenvironment

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Abstract:

目的：评价补肾调轴方改善IVF-ET反复种植失败者子宫免疫微环境的临床疗效。方法：将47例反复种植失败的患者作为研究对象，予补肾调轴方颗粒进行治疗，检测子宫内膜IDO的表达。结果：治疗后IDO的表达较治疗前提高，差异有统计学意义。结论：中药补肾调轴方能上调子宫内膜IDO的表达，促进胚胎免疫耐受，有助于胚胎的着床成功。
Objective: To evaluate the clinical efficacy of uterine immune microenvironment of Bushen Tiaozhou Recipe in IVF-ET repeated implant. Methods: 47 cases which failed implanting repeatedly were as the research objectives, and given Bushen Tiaozhou treatment; the expression of IDO was then tested. Results: The expression of IDO was higher after treatment. The difference was statistically significant. Conclusion: The traditional Chinese medicine recipe Bushen Tiaozhou can increase the expression of IDO. Besides, it can promote the embryo immune tolerance and help the embryo implantation success.

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