Larvae of several mosquito species being vectors of
infectious diseases as adults feed on algae in their natural habitat. Algal food comes along with bioactive
compounds providing important chemical defenses against predators, competitors,
and pathogens. Aedes aegypti (Linnaeus in Hasselquist, 1762) is commonly called yellow fever mosquito, being
a vector of several fatal diseases such as dengue fever, zika fever,
chikungunya, and yellow fever. In this study, we have investigated the
susceptibility of larvae of A. aegypti mosquitos to three most commonly studied diatom aldehydes-2-trans, 4-trans
heptadienal (HD), 2-trans, 4-trans octadienal (OD), and 2-trans,
4-trans-decadienal (DD). In the experiments, instar-I and -IV larvae of Ae. aegypti were exposed to above PUAs
for different time intervals. Both mosquito instars were susceptible to HD, OD
and DD. Instar-I larvae were more susceptible compared to instar-IV. The
percentage of mortality of both instar larvae was higher with greater
concentrations of each tested PUA. Furthermore, mosquito larvae, tested on DD
applied medium was estimated to be more susceptible followed by OD and then by
HD. After 24 h observation, LC 50 value was the lowest for DD (0.64 μL/40mL), followed by OD (0.88 μL/40mL) and HD
(1.47 μL/40mL) respectively. In current scenarios, our results suggest that natural
aldehydes from diatoms could provide promising public health benefits by
controlling mosquito vector populations. Furthermore, an in-depth study of
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