We dedicate to the 2D density-dependent nonhomogeneous incompressible Boussinesq equations with vacuum on . At infinity, if the attenuation of initial density and temperature is not very slow. And it is gained that there is a global strong solution and is unique for the 2D Cauchy problem with the initial density which can allow vacuum conditions and even have compact support. Besides, the large time decay rates of the gradients of velocity, temperature and pressure can also be obtained which are also the same as those of the homogeneous case.
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