Background and Objective: A systematic review of the epidemiology of cardiovascular risk factorssuch as hypertension, diabetes, hypercholesterolemia, obesity and smoking in three Latin American countries was carried out.Reliability and local representativeness of this information is fundamental for tailoring non-communicable disease control strategies to the context. Materials and Methods: Electronic databases and gray literature were searchedfor descriptive and cross-sectional population studies reporting prevalence of the above-mentioned risk factors in populations aged over 18 years in Peru, Ecuador and Bolivia, published between January 2000 and December 2017. Results: 29 articles,which together included a population of 38,271 individuals, were incorporated in the synthesis. A pooled prevalence was obtained for？each risk factor: smoking in men 37.60% [31.56 - 43.63] was the most frequent risk factor, followed by hypercholesterolemia 26.45% [18.89 - 34.02] and obesity in women 25.53% [19.78 - 31.29]. The Global prevalence of hypertension was 19.54% [15.34 - 23.74], similar for men and women (23.11; 23.26respectively).Conclusions:
References
[1]
General Assembly UN (2011) Political Declaration of the High-Level Meeting of the General Assembly on the Prevention and Control of Non-Communicable Diseases-Draft Resolution Submitted by the President of the General Assembly [Internet].
[2]
WHO (2014) Global Status Report on Noncommunicable Diseases. Geneva.
[3]
Anand, S.S. and Yusuf, S. (2011) Stemming the Global Tsunami of Cardiovascular Disease. The Lancet, 377, 529-532. https://doi.org/10.1016/S0140-6736(10)62346-X
[4]
Joseph, P., Leong, D., McKee, M., Anand, S.S., Schwalm, J.-D., Teo, K., et al. (2017) Reducing the Global Burden of Cardiovascular Disease, Part 1. Circulation Research, 121, 677-694. https://doi.org/10.1161/CIRCRESAHA.117.308903
[5]
Di Cesare, M., Khang, Y.-H., Asaria, P., Blakely, T., Cowan, M.J., Farzadfar, F., et al. (2013) Inequalities in Non-Communicable Diseases and Effective Responses. The Lancet (London, England), 381, 585-597.
https://doi.org/10.1016/S0140-6736(12)61851-0
[6]
Finegold, J.A., Asaria, P. and Francis, D.P. (2013) Mortality from Ischaemic Heart Disease by Country, Region, and Age: Statistics from World Health Organisation and United Nations. International Journal of Cardiology, 168, 934-945.
https://doi.org/10.1016/j.ijcard.2012.10.046
[7]
Chow, C.K., Teo, K., Rangarajan, S., Islam, S., Gupta, R., Avezum, A., et al. (2013) Prevalence, Awareness, Treatment, and Control of Hypertension in Rural and Urban Communities in High-, Middle-, and Low-Income Countries. JAMA, 310, 959.
https://doi.org/10.1001/jama.2013.184182
[8]
Barreto, S.M., Miranda, J.J., Figueroa, J.P., Schmidt, M.I., Munoz, S., Kuri-Morales, P.P., et al. (2012) Epidemiology in Latin America and the Caribbean: Current Situation and Challenges. International Journal of Epidemiology, 41, 557-571.
https://doi.org/10.1093/ije/dys017
[9]
Atun, R., Jaffar, S., Nishtar, S., Knaul, F.M., Barreto, M.L., Nyirenda, M., et al. (2013) Improving Responsiveness of Health Systems to Non-Communicable Diseases. The Lancet, 381, 690-697. https://doi.org/10.1016/S0140-6736(13)60063-X
[10]
NU CEPAL (2019) Panorama Social: Panor. Soc. América Lat. 2018. Santiago CEPAL 2019-02-07.
[11]
Higgins, J.P.T. and Green, S. (2011) Manual Cochrane de revisiones sistemáticas de intervenciones. Cochrane, 1-639. http://www.cochrane-handbook.org
[12]
Egger, M., Smith, G.D. and Altman, D.G. (2001) Systematic Reviews in Health Care [Internet]. Second. Syst. Rev. Heal. Care; Meta-Analysis Context. London.
https://doi.org/10.1002/9780470693926
[13]
Brockwell, S.E. and Gordon, I.R. (2001) A Comparison of Statistical Methods for Meta-Analysis. Statistics in Medicine, 20, 825-840. https://doi.org/10.1002/sim.650
[14]
Jacoby, E., Goldstein, J., López, A., Núnez, E. and López, T. (2003) Social Class, Family, and Life-Style Factors Associated with Overweight and Obesity among Adults in Peruvian Cities. Preventive Medicine, 37, 396-405.
https://doi.org/10.1016/S0091-7435(03)00159-2
[15]
Soto, V., Vergara, E. and Neciosup, E. (2005) Prevalencia y factores de riesgo de síndrome metabolico en poblacion adulta del departamento de Lambayeque, Peru 2004. Revista Peruana de Medicina Experimental y Salud Pública, 22, 254-261.
[16]
Goldstein, J., Jacoby, E., del Aguila, R. and Lopez, A. (2005) Poverty Is a Predictor of Non-Communicable Disease among Adults in Peruvian Cities. Preventive Medicine, 41, 800-806. https://doi.org/10.1016/j.ypmed.2005.06.001
[17]
Romero Seclen, G. (2005) Prevalencia e incidencia de consumo de tabaco en la población de Trujillo Metropolitano, La Libertad. MSc. Disseertation, Cayetano Heredia University.
[18]
Ochoa Sosa, S. (2005) Prevalencia e incidencia y factores asociados al consumo de tabaco en la población de 12 a 64 anos en la ciudad de Huancayo. MSc. Disseertation, Cayetano Heredia University.
[19]
Segura Vega, L., Regulo, A. and Parodi, J. (2006) Factores de Riesgo de las Enfermedades Cardiovasculares en el Perú. Revista Peruana de Cardiología, 32, 82-128.
[20]
Regulo Agusti, C. (2006) Epidemiología de la hipertensión arterial en el Perú. Acta Médica Peruana, 23, 69-75.
[21]
Gamarra, M. (2006) Prevalencia de diabetes mellitus, hipertensión arterial y obesidad en población adulta urbana (distrito de Wanchaq) y rural (distrito de Huancarani) del departamento del Cusco. MSc. Disseertation, Cayetano Heredia University.
[22]
Josefina, M., Julio, C.-M., Humberto, Z., Oscar, M., Juan, B., Fernando, C., Carolina, C., Zolila, V., Mauricio, P. and Munoz Edgar, C.-P.J. (2006) Estimaciones del Riesgo Cardiovascular Global en la Población Adulta de Arequipa Metropoli- tana: Resultados del Estudio Prevención. Revista Peruana de Cardiología, 32, 129-144.
[23]
Garcia, F., Solis, J., Luque, E., Neyra, L., Manrique, H., Cancino, R., et al. (2007) Prevalencia de diabetes mellitus y factores de riesgo relacionados en una población urbana. Revista Sociedad Peruana de Medicina Interna, 20, 90-94.
[24]
Medina-Lezama, J., Zea-Diaz, H., Morey-Vargas, O.L., Bolanos-Salazar, J.F., Munoz- Atahualpa, E., Postigo-MacDowall, M., et al. (2007) Prevalence of the Metabolic Syndrome in Peruvian Andean Hispanics: The PREVENCION Study. Diabetes Research and Clinical Practice, 78, 270-281.
https://doi.org/10.1016/j.diabres.2007.04.004
[25]
Damaso, B., Loza, C. and Menacho, L. (2007) Prevalencia del síndrome metabólico en trabajadores activos en la Red Asistencial de EsSalud en Huánuco. Scielo, 22, 21.
https://doi.org/10.20453/rmh.v22i2.1103
[26]
Medina-Lezama, J., Morey-Vargas, O.L., Zea-Díaz, H., Bolanos-Salazar, J.F., Corrales-Medina, F., Cuba-Bustinza, C., et al. (2008) Prevalence of Lifestyle-Related Cardiovascular Risk Factors in Peru: The PREVENCION Study. Pan American Journal of Public Health, 24, 169-179.
https://doi.org/10.1590/S1020-49892008000900003
[27]
Medina, J., Chirinos, J., Zea, H., Morey, O., Bolanos, J., Cuba, C., et al. (2009) Aspectos epidemiológicos y hemodinámicos de la hipertensión y de la prehiper- tensión arterial en Arequipa. Resultados del estudio Prevención. Revista Peruana de Cardiología, 35, 30-43.
[28]
Pajuelo Ramirez, J. and Sanchez Abanto, J. (2010) Estado Nutricional del adulto en relación al riesgo cardiovascular. Revista de La Sociedad Peruana de Medicina Interna, 23, 85-91.
[29]
Miranda, J.J., Gilman, R.H. and Smeeth, L. (2011) Differences in Cardiovascular Risk Factors in Rural, Urban and Rural-to-Urban Migrants in Peru. Heart, 97, 787- 796. https://doi.org/10.1136/hrt.2010.218537
[30]
Weygandt, P.L., Vidal-Cardenas, E., Gilman, R.H., Avila-Tang, E., Cabrera, L. and Checkley, W. (2012) Epidemiology of Tobacco Use and Dependence in Adults in a Poor Peri-Urban Community in Lima, Peru. BMC Pulmonary Medicine, 12, 9.
https://doi.org/10.1186/1471-2466-12-9
[31]
Prince, M.J., Ebrahim, S., Acosta, D., Ferri, C.P., Guerra, M., Huang, Y., et al. (2012) Hypertension Prevalence, Awareness, Treatment and Control among Older People in Latin America, India and China: A 10/66 Cross-Sectional Population-Based Survey. Journal of Hypertension, 30, 177-187.
https://doi.org/10.1097/HJH.0b013e32834d9eda
[32]
Guffanti, G. and Maldonado, V. (2000) 2. Factores de riesgo cardiovascular modificables Dislipidemia—Obesidad en trabajadores de la salud. Hospital Quito de la Policía Nacional 1999-2000. Revista Médica Hospital Quito Policia Nacional, 6, 34-42.
[33]
Sánchez, P. and Lisanti, N. (2003) The Prevalence of and Attitudes toward Smoking among Physicians in Azuay, Ecuador. Pan American Journal of Public Health, 14, 25-30. https://doi.org/10.1590/S1020-49892003000600005
[34]
Hidalgo, L.A., Chedraui, P.A., Morocho, N., Alvarado, M., Chavez, D. and Huc, A. (2006) The Metabolic Syndrome among Postmenopausal Women in Ecuador. Gynecological Endocrinology: The Official Journal of the International Society of Gynecological Endocrinology, 22, 447-454.
https://doi.org/10.1080/09513590600890272
[35]
Sempértegui, F., Estrella, B., Tucker, K.L., Hamer, D.H., Narvaez, X., Sempértegui, M., et al. (2011) Metabolic Syndrome in the Elderly Living in Marginal Peri-Urban Communities in Quito, Ecuador. Public Health Nutrition, 14, 758-767.
https://doi.org/10.1017/S1368980010002636
[36]
Torres, M., Ortiz, R., Siguencia, W., Ortiz, A., Anez, R., et al. (2013) Prevalencia de la obesidad en individuos adultos en las parroquias urbanas de la ciudad de Cuenca, Ecuador. Síndrome Cardiometabólico, 3, 76-84.
[37]
Ortiz Benavides, R., Ortiz Benavides, A., Villalobos, M., Rojas, J., Torres Valdez, M., Siguencia Cruz, W., et al. (2014) Prevalencia de hipertensión arterial en individuos adultos de las parroquias urbanas de la ciudad de Cuenca, Ecuador. Síndrome Cardiometabólico, 4, 10-21.
[38]
Ortiz, R., Bermúdez, V., Guzmán, J., Silva, J., Torres, M., Carvajal, J., et al. (2017) Hipertensión arterial y su comportamiento epidemiológico en la población rural de Cumbe, Ecuador. Revista Latinoamericana de Hipertensión, 12, 109-118.
[39]
Tarifa, W. (2005) Prevalencia y factores asociados a hipertensión arterial en la ciudad de El Alto, 2004. MSc. Disseertation, Universidad Mayor de San Andrés.
[40]
Gutiérrez, A., Salazar, J., Méndez, A. and Rocha, K. (2006) Prevalencia de factores de riesgo coronarios en adultos jóvenes estudiantes de la UMSA de la ciudad de La Paz, 2005. Revista Cuadernos, 5, 34-40.
[41]
Royer, M., Castelo-Branco, C., Blümel, J.E., Chedraui, P.A., Danckers, L., Bencosme, A., et al. (2007) The US National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III): Prevalence of the Metabolic Syndrome in Postmenopausal Latin American Women. Climacteric: The Journal of the International Menopause Society, 10, 164-170. https://doi.org/10.1080/13697130701258895
[42]
Schargrodsky, H., Hernández-Hernández, R., Champagne, B.M., Silva, H., Vinueza, R., Silva Aycaguer, L.C., et al. (2008) CARMELA: Assessment of Cardiovascular Risk in Seven Latin American Cities. The American Journal of Medicine, 121, 58-65.
https://doi.org/10.1016/j.amjmed.2007.08.038
[43]
WHO (2018) Noncommunicable Diseases Progress Monitor 2017.
[44]
Stanaway, J.D., Afshin, A., Gakidou, E., Lim, S.S., Abate, D., Abate, K.H., et al. (2018) Global, Regional, and National Comparative Risk Assessment of 84 Behavioural, Environmental and Occupational, and Metabolic Risks or Clusters of Risks for 195 Countries and Territories, 1990-2017: A Systematic Analysis for the Global Burden of Disease Study 2017. The Lancet, 392, 1923-1994.
https://doi.org/10.1016/S0140-6736(18)32225-6
[45]
De Maio, F.G. (2011) Understanding Chronic Non-Communicable Diseases in Latin America: Towards an Equity-Based Research Agenda. Globalization and Health, 7, 36. https://doi.org/10.1186/1744-8603-7-36
[46]
Pan American Health Organization (2017) Health in the Americas Summary: Regional Outlook and Country Profiles. Health in Pan American Health Organization, Washington DC.
[47]
International Diabetes Federation (2015) IDF Diabetes Atlas. 7th Edition.
[48]
Marmot, M. and Bell, R. (2019) Social Determinants and Non-Communicable Diseases: Time for Integrated Action. BMJ, 364, 1251. https://doi.org/10.1136/bmj.l251
[49]
Yusuf, S., Reddy, S., Ounpuu, S. and Anand, S. (2001) Global Burden of Cardiovascular Diseases. Part I: General Considerations, the Epidemiologic Transition, Risk Factors, and Impact of Urbanization. Circulation, 104, 2746-2753.
https://doi.org/10.1161/hc4601.099487
[50]
Yusuf, S., Reddy, S., Ounpuu, S. and Anand, S. (2001) Global Burden of Cardiovascular Diseases Part II: Variations in Cardiovascular Disease by Specific Ethnic Groups and Geographic Regions and Prevention Strategies. Circulation, 104, 2855- 2864. https://doi.org/10.1161/hc4701.099488
[51]
Swingler, G.H., Volmink, J. and Ioannidis, J.P.A. (2003) Number of Published Systematic Reviews and Global Burden of Disease: Database Analysis. BMJ, 327, 1083- 1084. https://doi.org/10.1136/bmj.327.7423.1083
[52]
Homedes, N. and Ugalde, A. (2014) Clinical Trials in Latin America: Where Ethics and Business Clash. Springer International Publishing, Cham.
https://doi.org/10.1007/978-3-319-01363-3
[53]
Benavides Ordónez, J. (2018) The Amendment Procedures in Some Constitution of Latin America. A Normative Study with Particular Emphasis on the Ecuadorian Constitution of 2008. Estudios Constitucionales, 16, 39-66.
https://doi.org/10.4067/S0718-52002018000100039
[54]
Viciano Pastor, R. and Martínez Dalmau, R. (2016) Los procesos constituyentes Latinoamericanos y el nuevo paradigma Constitucional. REVISTA IUS, 4.
https://doi.org/10.35487/rius.v4i25.2010.214
[55]
Ordunez, P., Martinez, R., Niebylski, M.L. and Campbell, N.R. (2015) Hypertension Prevention and Control in Latin America and the Caribbean. The Journal of Clinical Hypertension, 17, 499-502. https://doi.org/10.1111/jch.12518
[56]
Anselmi, M., Araujo, E., Narváez, A., Cooper, P.J. and Guderian, R.H. (1995) Yaws in Ecuador: Impact of Control Measures on the Disease in the Province of Esmeraldas. Genitourinary Medicine, 71, 343-346. https://doi.org/10.1136/sti.71.6.343
[57]
Anselmi, M., Avanzini, F., Moreira, J.M., Montalvo, G., Armani, D., Prandi, R., et al. (2003) Treatment and Control of Arterial Hypertension in a Rural Community in Ecuador. The Lancet, 361, 1186-1187.
https://doi.org/10.1016/S0140-6736(03)12918-2
[58]
CSDH (2008) Closing the Gap in a Generation: Health Equity through Action on the Social Determinants of Health. World Health Organization, Geneva.
[59]
Economic Commission for Latin America and the Caribbean (ECLAC) (2017) Annual Report on Regional Progress and Challenges in Relation to the 2030 Agenda for Sustainable Development in Latin America and the Caribbean. Santiago.
[60]
Hogan, D.R., Stevens, G.A., Hosseinpoor, A.R. and Boerma, T. (2018) Monitoring Universal Health Coverage within the Sustainable Development Goals: Development and Baseline Data for an Index of Essential Health Services. The Lancet Global Health, 6, e152-e168. https://doi.org/10.1016/S2214-109X(17)30472-2
[61]
Reddy, K.S. (2016) Global Burden of Disease Study 2015 Provides GPS for Global Health 2030. The Lancet, 388, 1448-1449.
https://doi.org/10.1016/S0140-6736(16)31743-3
