Pulmonary embolism following upper limb surgery is a very rare complication.
Here we present a unique case report of a 54-year-old young, fit and
healthy, and non-smoker male who developed bilateral pulmonary embolism
(PE) 26 days post-operatively with no associated upper or lower limb Deep
Vein Thrombosis (DVT). This patient had minimal preoperative as well as
intra-operative risk factors. He did not develop any thromboembolic symptoms
until the 26th-day post-surgery when he developed sudden, sharp, pleuritic
chest pain and laboured breathing. Initial baseline bloods showed a
raised D-Dimer and the patient subsequently had a CT pulmonary angiogram
that confirmed the presence of bilateral massive PEs. However, subsequent
extremity ultrasound showed no upper or lower deep venous thrombosis.
Thorough review of literature suggests that sudden development of PEs after
upper limb surgery is possible, with a few cases being reported in the past.
Symptoms such as sudden upper limb swelling, troubled breathing and systemic
symptoms should be evaluated aggressively with a CT pulmonary angiogram,
given the fact that an ultrasound of the extremities may be negative
for deep venous thrombosis.
References
[1]
Perrier, A. (1997) Noninvasive Diagnosis of Pulmonary Embolism. Heamatologica, 82, 328-331.
[2]
Kearon, C., Akl, E.A., Comerota, A.J., Prandoni, P., Bounameaux, H., Goldhaber, S.Z., Nelson, M.E., Wells, P.S., Gould, M.K., Dentali, F., Crowther, M. and Kahn, S.R. (2012) American College of Chest Physicians. Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest, 141, e419S-e496S.
https://doi.org/10.1378/chest.11-2301
[3]
Nakamura, K., Tachibana, S., Fuji, T., Akagi, M., Abe, Y., Ikeda, N., Ishii, S., Kobayashi, S., Sato, T., Nakamura, S., Higuchi, F., Fujita, S. and Yanagimoto, S. (2008) Japanese Orthopaedic Association (JOA) Clinical Practice Guideline on the Prevention of Venous Thromboembolism in Patients Undergoing Orthopaedic Treatments. 1. Nankodo, Tokyo. (In Japanese)
[4]
Willis, A.A., Warren, R.F., Craig, E.V., et al. (2009) Deep Venous Thrombosis after Reconstructive Shoulder Arthroplasty: A Perspective Observational Study. Journal of Shoulder and Elbow Surgery, 18, 100-106.
https://doi.org/10.1016/j.jse.2008.07.011
[5]
National Institute for Health and Clinical Excellence (2007) Reducing the Risk of Venous Thromboembolism (Deep Vein Thrombosis and Pulmonary Embolism) in Inpatients Undergoing Surgery. NICE Clinical Guideline, No-46.
[6]
Tapson, V.F., Carroll, B.A., Davidson, B.L., et al. (1999) The Diagnostic Approach to Acute Venous Thromboembolism. Clinical Practice Guidelines. American Journal of Respiratory and Critical Care Medicine, 160, 1043-1066.
https://doi.org/10.1164/ajrccm.160.3.16030
[7]
Michiels, J.J., Gadisseur, A., van der Planken M., et al. (2005) A Critical Appraisal of Non-Invasive Diagnosis and Exclusion of Deep Vein Thrombosis and Pulmonary Embolism in Outpatients with Suspected Deep Vein Thrombosis and Pulmonary Embolism: How Many Test Do We Need? International Angiology, 24, 27-39.