Background: There are no studies of death from neurological diseases found,
however, neurological diseases were the leading cause of disability-adjusted
life years in 2015 worldwide. Aim: The scientific aim of this study is to analyze
the death characteristics of neurological diseases in Inner Mongolia occurring
between 2008 and 2015. Methods: The data collected from Death Registry
System (DRS) were categorized by gender, ethnicity, age, and death location.
The subjects were divided into age groups for every 10 years from the
age of 20. Mortality and gender: age-specific mortality was calculated for
every 100,000 people from 2008 to 2015. Results: We found that Alzheimer’s
disease has the highest proportion which equated to over one-fifth of all neurological
diseases. Males displayed a higher mortality rate than females in all
neurological diseases. The neurological diseases mortality showed a total potential
year of life lost (PYLL) of about 20,151 years, and it was 2.03 times
higher for male than that for female. The average potential years of life lost
(APYLL) showed 17.72 years, and APYLL in males was 3.34 years longer than
in females. More than 60% of the deaths resulting from the neurological disease
occur at home for both males and females. Conclusion: Alzheimer disease
is the most serious disease of all neurological diseases, however, cerebral
palsy and epilepsy also displayed the highest loss of life for residents. Mortality
of neurological diseases was generally higher in males than in females, and
this increased with age.
References
[1]
WHO (2008) élargir l’ accès aux soins pour lutter contre les troubles mentaux, neurologiques et liés à l’utilisation de substances psychoactives. https://www.who.int/mental_health/mhgap_french.pdf
[2]
Akhvlediani, T., Bautista, C.T., Shakarishvili, R., Tsertsvadze, T., Imnadze, P., et al. (2014) Etiologic Agents of Central Nervous System Infections among Febrile Hospitalized Patients in the Country of Georgia. PLoS ONE, 9, e111393. https://doi.org/10.1371/journal.pone.0111393
[3]
Sejvar, J. (2014) Neuroepidemiology and the Epidemiology of Viral Infections of the Nervous System. Handbook of Clinical Neurology, 123, 67-87. https://doi.org/10.1016/B978-0-444-53488-0.00003-1
[4]
Feigin, V.L., Abajobir, A.A., Abate, K.H., Abdallah, F., Abdulle, A.M., Abera, S.F., et al. (2017) Global, Regional, and National Burden of Neurological Disorders during 1990-2015: A Systematic Analysis for the Global Burden of Disease Study 2015. The Lancet Neurology, 16, 877-897.
[5]
Senanayake, N. and Román, G.C. (1993) Epidemiology of Epilepsy in Developing Countries. Bulletin of the World Health Organization, 71, 247-258.
[6]
Mollaoğlu, M., Fertelli, T.K. and Tuncay, F.Ö. (2011) Disability in Elderly Patients with Chronic Neurological Illness: Stroke, Multiple Sclerosis and Epilepsy. Archives of Gerontology & Geriatrics, 53, e227-e231. https://doi.org/10.1016/j.archger.2010.11.031
[7]
Xin, K.-P., et al. (2014) Colorectal Cancer Mortality in Inner Mongolia between 2008 and 2012. World Journal of Gastroenterology, 20, 8209-8214. https://doi.org/10.3748/wjg.v20.i25.8209
[8]
Ramasamy, A., Trabzuni, D., Guelfi, S., Varghese, V., Smith, C., Walker, R., et al. (2014) Genetic Variability in the Regulation of Gene Expression in Ten Regions of the Human Brain. Nature Neuroscience, 17, 1418-1428. https://doi.org/10.1038/nn.3801
[9]
Yancik, R., Wesley, M.N., Ries, L.A.G., et al. (1998) Comorbidity and Age as Predictors of Risk for Early Mortality of Male and Female Colon Carcinoma Patients: A Population-Based Study. Cancer, 82, 2123-2134. https://doi.org/10.1002/(SICI)1097-0142(19980601)82:11<2123::AID-CNCR6>3.0.CO;2-W
[10]
Leestma, J., Walczak, T., Hughes, J.R., Kalelkar, M.B. and Teas, S.S. (1989) A Prospective Study on Sudden Unexpected Death in Epilepsy. Annals of Neurology, 26, 195-203. https://doi.org/10.1002/ana.410260203
[11]
Selkoe, D.J. (2007) Developing Preventive Therapies for Chronic Diseases: Lessons Learned from Alzheimer’s Disease. Nutrition Reviews, 65, S239-S243. https://doi.org/10.1111/j.1753-4887.2007.tb00370.x
[12]
Plesca, D., Houssein Toufic, S., Dinu, I. and Safer, M. (2014) PO-0853 Quality of Life in Children with Cerebral Palsy and Adhd before and after Administration of Treatment. Archives of Disease in Childhood, 99, A530-A531. https://doi.org/10.1136/archdischild-2014-307384.1479
[13]
Bon, O.L., Fischler, B., Hoffmann, G., Murphy, J.R. and Pelc, I. (2000) How Significant Are Primary Sleep Disorders and Sleepiness in Chronic Fatigue Syndrome? Sleep Research Online: SRO, 3, 43-48.