All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99

ViewsDownloads

Relative Articles

More...

Efficient Particle Separation in Microfluid Channel with Inhomogeneous Magnetic Field

DOI: 10.4236/jemaa.2019.112002, PP. 17-23

Keywords: Particle Separation, Efficient Separation, Microfluid Channel, Inhomogeneous Magnetic Field

Full-Text   Cite this paper   Add to My Lib

Abstract:

In this paper, we combined magnetostatics and laminar flow in microfluidics and studied a particle separation scheme employing magnetophoretic force in inhomogeneous magnetic field. A detailed model and analysis is shown and the proposed scheme is capable of efficiently separating magnetic particles with different permeability and sizes. The method shows a way to separate efficient particles and could potentially be implemented in biological and chemical systems.

References

[1]  Huh, D., Bahng, J.H., Ling, Y., Wei, H.-H., Kripfgans, O.D., Fowlkes, J.B., Grotberg, J.B. and Takayama, S. (2007) Gravity-Driven Microfluidic Particle Sorting Device with Hydrodynamic Separation Amplification. Analytical Chemistry, 79, 1369-1376.
https://doi.org/10.1021/ac061542n
[2]  Petersson, F., Åberg, L., Swärd-Nilsson, A.-M. and Laurell, T. (2007) Free Flow Acoustophoresis: Microfluidic-Based Mode of Particle and Cell Separation. Analytical Chemistry, 79, 5117-5123.
https://doi.org/10.1021/ac070444e
[3]  Gossett, D.R., Weaver, W.M., Mach, A.J., Hur, S.C., Tse, H.T.K., Lee, W., Amini, H. and Di Carlo, D. (2010) Label-Free Cell Separation and Sorting in Microfluidic Systems. Analytical and Bioanalytical Chemistry, 397, 3249-3267.
https://doi.org/10.1007/s00216-010-3721-9
[4]  Bhagat, A.A.S., Bow, H., Hou, H.W., Tan, S.J., Han, J. and Lim, C.T. (2010) Microfluidics for Cell Separation. Medical & Biological Engineering & Computing, 48, 999-1014.
https://doi.org/10.1007/s11517-010-0611-4
[5]  Xia, N., Hunt, T.P., Mayers, B.T., Alsberg, E., Whitesides, G.M., Westervelt, R.M. and Ingber, D.E. (2006) Combined Microfluidic-Micromagnetic Separation of Living Cells in Continuous Flow. Biomedical Microdevices, 8, 299.
https://doi.org/10.1007/s10544-006-0033-0
[6]  Gascoyne, P.R.C. and Vykoukal, J. (2002) Particle Separation by Dielectrophoresis. Electrophoresis, 23, 1973-1983.
https://doi.org/10.1002/1522-2683(200207)23:13<1973::AID-ELPS1973>3.0.CO;2-1
[7]  Kuntaegowdanahalli, S.S., Bhagat, A.A.S., Kumar, G. and Papautsky, I. (2009) Inertial Microfluidics for Continuous Particle Separation in Spiral Microchannels. Lab on a Chip, 9, 2973-2980.
https://doi.org/10.1039/b908271a
[8]  Sajeesh, P. and Sen, A.K. (2014) Particle Separation and Sorting in Microfluidic Devices: A Review. Microfluidics and Nanofluidics, 17, 1-52.
https://doi.org/10.1007/s10404-013-1291-9
[9]  De Sarabia, E.R.-F., Gallego-Juárez, J.A., Rodríguez-Corral, G., Elvira-Segura, L. and González-Gómez, I. (2000) Application of High-Power Ultrasound to Enhance Fluid/Solid Particle Separation Processes. Ultrasonics, 38, 642-646.
https://doi.org/10.1016/S0041-624X(99)00129-8
[10]  Inglis, D.W. (2009) Efficient Microfluidic Particle Separation Arrays. Applied Physics Letters, 94, 013510.
https://doi.org/10.1063/1.3068750
[11]  Ida, N. (2000) Engineering Electromagnetics. Vol. 2. Springer, New York.
https://doi.org/10.1007/978-1-4757-3287-0
[12]  Furlani, E.P. and Sahoo, Y. (2006) Analytical Model for the Magnetic Field and Force in a Magnetophoretic Microsystem. Journal of Physics D: Applied Physics, 39, 1724.
https://doi.org/10.1088/0022-3727/39/9/003
[13]  Gerhart, P.M., Gerhart, A.L. and Hochstein, J.I. (2016) Munson, Young and Okiishi’s Fundamentals of Fluid Mechanics, Binder Ready Version. John Wiley & Sons, Hoboken.

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133

WeChat 1538708413