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- 2018
补黄四五汤治疗周围性面瘫的疗效及安全性
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Abstract:
摘要 目的 观察陈宝田教授经验方补黄四五汤治疗周围性面瘫的疗效及安全性.方法 选择符合标准的100例患者,随机分为2组,每组各50例,治疗组予补黄四五汤治疗,对照组予常规西药治疗,比较两组的疗效并进行安全性评价.结果 治疗组治愈率为44%、总有效率为92%,对照组治愈率为16%、总有效率为54%,两组治愈率及总有效率均有统计学差异(P<0.05).两组治疗前后Portmann简易评分,眼轮匝肌与口轮匝肌M波潜伏期差值、患健侧M波的波幅比、瞬目反射患侧R1、R2、R2'未出波率及其潜伏期有统计学差异(P<0.05),且治疗后治疗组与对照组之间各项指标有统计学差异(P<0.05).治疗组不良反应为腹泻,发生率为18%,可自行缓解或加入番石榴叶后消失,对照组不良反应为口干、食欲不振、面部痤疮,发生率为26%.结论 补黄四五汤与西医常规治疗均能显著改善周围性面瘫患者症状及面神经功能,且补黄四五汤疗效显著优于常规西药,安全性相对较高.
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