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-  2015 

2种茶叶多糖降血糖效果的比较
Hypoglycemic effects of two tea polysaccharides

Keywords: 茶多糖 茶树品种 降血糖 糖尿病
tea polysaccharides tea varieties hypoglycemic activity diabetes

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Abstract:

研究迎霜茶多糖(T01-TPS)和云南大叶种茶多糖(T09-TPS)对四氧嘧啶致糖尿病小鼠的降血糖作用。对正常小鼠和四氧嘧啶造模的高血糖小鼠分别经过灌胃给予2种茶多糖14 d,测定给药前后小鼠的空腹血糖值、体质量与免疫器官质量,进行糖耐量试验。结果表明:迎霜茶多糖和云南大叶种茶多糖均能较好地降低糖尿病小鼠血糖水平,表现出一定的量效关系,并能减缓糖尿病小鼠多食、多饮和消瘦症状;2种茶多糖能使糖尿病小鼠的血糖曲线下面积明显下移,提高糖尿病模型小鼠的葡萄糖耐量;可使糖尿病小鼠的胸腺指数和脾脏指数提高,促进糖尿病小鼠脾脏和胸腺的发育,说明2种茶多糖具有明显的降血糖作用和一定的增强免疫调节能力的作用,迎霜茶多糖效果优于云南大叶种茶多糖。
Effects of T01-TPS extracted from Yingshuang (Camellia sinensis) and T09-TPS extracted from Yunnan Dayezhong (Camellia sinensis) on alloxan-induced diabetes mice were studied.Different groups of normal mice and diabetic mice induced by alloxan were administered TPS for 14 days.Fasting blood glucose,weight of body,and immune organs were determined before and after treatment.The glucose tolerance tests were carried out.The results showed that both T01-TPS and T09-TPS significantly decreased the blood glucose level in alloxan-induced mice which was correlated with the dosage of TPS to some degree and increased the glucose tolerance in alloxan-induced mice.Both T01-TPS and T09-TPS improved the index of thymus and spleen.It is indicated that T01-TPS and T09-TPS had remarkable hypoglycemic effect and immune-enhancing activity.The effect of T01-TPS was better than that of T09-TPS.

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