徐州农村地区胃癌高危人群干预效果分析*
Intervention efficacy of gastric cancer high-risk population from rural areas of Xuzhou City

目的:评价农村胃癌高危人群综合干预措施的效果。方法:从徐州农村地区选择胃癌高危人群257人进行干预。干预措施包括药物干预和行为干预。干预6个月之后,利用调查问卷收集资料,评价胃癌防治知识及胃癌预测因素的变化。干预1 a后,89人复查幽门螺杆菌感染,111人复查胃镜,依据复查结果评价幽门螺杆菌感染和胃部疾病改善情况。结果:干预后,三餐规律性、腌制食物食用频率、辛辣食物食用习惯、每月食盐量、饮酒习惯等因素较干预前有改善(P＜0.05); 幽门螺杆菌感染率由干预前的58.4%下降到干预后的40.4%(P=0.002),好转20人(22.4%),无效65人(73.0%),加重4人(4.5%)。胃镜检查结果好转34人(30.6%),无效77人(69.4%)。结论:对农村胃癌高危人群实施行为干预和药物干预,可以提高人群的胃癌防治知识水平,有效控制胃癌前疾病的发生发展。
Aim: To assess the intervention efficacy of the gastric cancer high-risk population from rural area of Xuzhou City.Methods: A total of 257 cases intervened by medical and behavior intervention were followed up through telephone in Xuzhou City. After 6 month intervention,data were collected by questionnaire survey, and the changes of the awareness of prevention knowledge about gastric cancer and cancer risk factors were evaluated. After 1 a, 111 cases were under went the endoscopy and 89 were reviewed for Hp infection, and the situation of improvement of gastric diseases were assessed.Results: The survey revealed that regular meals, pickled food consumption frequency, spicy food eating habits, daily salt consumption, and drinking habits of the villagers had been improved(P＜0.05). Hp-infected rate was reduced from 58.4% to 40.4%(P=0.002), with improved in 20 cases, ineffective in 65 cases, and aggravated in 4 cases. The results of endoscopy showed that the symptoms improved in 34 cases and not improved or progressed in 77 cases.Conclusion: Implementation of behavioral intervention and drug intervention in rural high-risk population of gastric cancer can effectively improve the gastric cancer prevention and control knowledge, so that prevent and control the occurrence and development of gastric precancerous diseases