荨麻疹患者1 355例血清特异性IgE检测及过敏原分析
Analysis of serum allergen-specific IgE in 1 355 patients with urticaria

目的:通过特异性IgE(sIgE)检测分析荨麻疹患者过敏原的分布特点。方法:采用ELISA法对1 355例荨麻疹患者进行血清过敏原sIgE检测。结果:1 355例荨麻疹患者过敏原sIgE阳性检出率为69.0%(935例),sIgE阳性检出率较高的吸入性过敏原主要为霉菌(21.5%)、螨(17.4%)和梧桐花粉(14.2%),食物性过敏原主要为鸡蛋(23.5%)和花生(13.1%)。男性患者总IgE增高者检出率高于女性(P<0.001)。13～18岁年龄段人群sIgE检出率达到峰值。结论:荨麻疹患者过敏原以霉菌、鸡蛋、尘螨为主,过敏情况存在性别、年龄差异。
Aim:To explore the prevalence of serum allergen-specific IgE in patients with urticaria.Methods:The serum allergen-specific IgE of 1 355 patients with urticaria was detected by ELISA.Results:The positive rate of allergen-specific IgE in 1 355 patients was 69.0%; the most common inhale allergens were mold(21.5%), mites(17.4%)and phoenix tree pollen(14.2%); while the corresponding ingested allergens were eggs(23.5%)and peanuts(13.1%). The positive rate of total IgE in male patients was higher than that in females(P<0.001). The positive rate of total IgE got to the peak stage in the patients aged 13-18 years.Conclusion:The main allergens of urticaria patients are mold, eggs and mites, and the status of the patients varied by sex and age