剪切波弹性成像与乳腺X线摄影对乳腺肿块诊断价值的比较
Comparison of the value of shear wave elastography and digital mammography in differential diagnosis of breast neoplasms

摘要：目的 比较剪切波弹性成像(SWE)与乳腺X线摄影对乳腺良、恶性肿块的鉴别诊断价值。方法 对96个乳腺病灶术前行SWE和乳腺X线摄影检查。SWE采用最大弹性模量值(E-max)进行评估。以病理结果为金标准，比较两种技术诊断乳腺病变的效能。结果 E-max诊断乳腺恶性病变的敏感性、特异性、准确性、阳性和阴性预测值分别为91.3%、94.0%、92.7%、93.3%、92.1%；Emax的敏感性和准确性均高于乳腺X线摄影(P均<0.05)。Emax诊断乳腺良、恶性病灶的受试者特征曲线下面积为0.983(95% CI，0.963～0.998)。结论 SWE在诊断乳腺良、恶性病灶时较乳腺X线摄影更有价值。
ABSTRACT: Objective To compare the value of shear wave elastography (SWE) and mammography in differential diagnosis of benign and malignant breast neoplasms. Methods Totally 96 patients with breast tumor were randomly chosen and underwent SWE andmammography. The elastic maximum value (Emax) was obtained. Taking histological diagnosis as the golden standards, we compared the two techniques’ sensitivity, specificity, accuracy, positive and negative predictive value in diagnosis of breast tumors. Results The sensitivity, specificity, accuracy, positive and negative predictive value of Emax were 91.3%, 94.0%, 92.7%, 93.3% and 92.1%, respectively. The sensitivity and accuracy of E-max were significantly better than those of x-ray (both P<0.05). The area under the ROC curve of Emax was 0.983 (95%CI, 0.963 to 0.998). Conclusion SWE outperforms mammography in differential diagnosis of benign and malignant breast tumors