1-甲基-6,7-二羟基-1,2,3,4-四氢异喹啉（Sal）是一种儿茶酚异喹啉类物质，主要存在于哺乳动物脑内并执行多种生理功能。通过机体代谢，Sal 可转变成为内源性神经毒素参与帕金森病（PD）的发生，由此引发学者的广泛关注。近年的研究显示，Sal 还参与酒精成瘾的形成以及影响神经内分泌系统相关激素的释放，是潜在的多巴胺能神经元调节因子。本文从以上几方面展开探讨 Sal 的神经生物学功能，为深入研究其具体作用机制提供理论支持
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