针对传统脉搏波传导时间(PTT)检测方法对脉搏波(PPG)信号幅值变化敏感、计算量大等问题,提出了一种综合波形时域特征和动态差分阈值的 PTT 检测算法。采用动态差分阈值检测心电(ECG)信号 R 波,根据波形时域特征缩短脉搏波信号主波检测区间,利用 R 波检测脉搏波信号主波,从而计算 PTT。利用美国麻省理工学院 MIMIC 数据库和实验室实测数据对上述算法进行验证。结果表明,该方法能够准确地提取特征点并检测出 PTT,对实测和数据库样本的 PTT 检测准确率分别为 99.1% 和 97.5%,效果优于传统检测方法
3. Sugo Y, Ukawa T, Takeda S, et al. A novel continuous cardiac output monitor based on pulse wave transit time. Conf Proc IEEE Eng Med Biol Soc, 2010, 2010(10): 2853-2856.
[4]
4. Hruda J, Chobola M, Lukes M, et al. Pulse wave transit time technique for perioperative non-invasive hemodynamic monitoring. Critical Care, 2014, 18(S1): 1-182.
[5]
5. Kang J E, Song I K, Lee J H, et al. Pulse Transit time shows vascular changes caused by propofol in children. J Clin Monit Comput, 2015, 29(4): 533-537.
[6]
6. Hennig A, Patzak A. Continuous blood pressure measurement using pulse transit time. Somnologie-Schlafforschung und Schlafmedizin, 2013, 17(2): 104-110.
8. Zakaria N A, Sharifmuddin N B, Ridzwan W M F W M, et al. Pulse wave transit time and its relationship with systolic blood pressure//6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore. Springer Berlin Heidelberg, 2010: 1354-1357.
[9]
9. Gesche H, Grosskurth D, Küchler G, et al. Continuous blood pressure measurement by using the pulse transit time: comparison to a cuff-based method. Eur J Appl Physiol, 2012, 112(1): 309-315.
[10]
10. Choi Y, Zhang Q, Ko S. Noninvasive cuffless blood pressure estimation using pulse transit time and Hilbert-Huang transform. Conf Proc IEEE Eng Med Biol Soc, 2013, 39(1): 103-111.