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-  2017 

应用血流向量成像技术研究原发性高血压左室能量损耗

DOI: doi:10.7507/1001-5515.201607026

Keywords: 血流向量成像技术, 左室能量损耗, 高血压, 心功能

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Abstract:

本研究旨在运用血流向量成像技术(VFM)研究原发性高血压患者左心室能量损耗差异,尽早检出流场力学异常的高血压患者,早期预防靶器官损害,并初步探索反映原发性高血压患者心脏舒缩功能变化的新方法。纳入健康志愿者 22 例、左室心肌质量指数(LVMI)正常的高血压患者 14 例及 LVMI 升高的高血压患者 21 例作为研究对象,分别行常规超声心动图、VFM 检查及双频脉冲多普勒检查。结果显示高血压病例组的左室能量损耗明显高于正常组(P<0.05),且舒张期能量损耗=0.439×SBP(收缩压)–8.349,收缩期能量损耗=0.385×SBP+0.644×LVMI–10.854;左室舒缩期能量损耗与 E/e' 相关,但与左室射血分数(EF)不相关。研究表明左室能量损耗有助于发现高血压患者流场力学变化;左室能量损耗变化是否能成为评估左室舒张功能的新指标,尚需深入研究;SBP 是舒张期能量损耗的独立预测因素,LVMI 及 SBP 是收缩期能量损耗的独立预测因素

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